Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 12/3/21 1:30 PM | 12/3/21 1:30 PM | 1. FC Union Berlin | RB Leipzig | 2-1 | 5 - 5 - 3 |
| 12/4/21 8:30 AM | 12/4/21 8:30 AM | FSV Mainz 05 | VfL Wolfsburg | 3-0 | 4 - 5 - 4 |
| 12/4/21 8:30 AM | 12/4/21 8:30 AM | 1899 Hoffenheim | Eintracht Frankfurt | 3-2 | 3 - 6 - 5 |
| 12/4/21 8:30 AM | 12/4/21 8:30 AM | Bayer 04 Leverkusen | SpVgg Greuther Fürth | 7-1 | 3 - 6 - 6 |
| 12/4/21 8:30 AM | 12/4/21 8:30 AM | Arminia Bielefeld | 1. FC Köln | 1-1 | 6 - 4 - 4 |
| 12/4/21 8:30 AM | 12/4/21 8:30 AM | FC Augsburg | VfL Bochum | 2-3 | 3 - 6 - 6 |
| 12/4/21 11:30 AM | 12/4/21 11:30 AM | Borussia Dortmund | FC Bayern Munich | 2-3 | 6 - 5 - 3 |
| 12/5/21 8:30 AM | 12/5/21 8:30 AM | VfB Stuttgart | Hertha BSC | 2-2 | 3 - 5 - 6 |
| 12/5/21 10:30 AM | 12/5/21 10:30 AM | Bor. Mönchengladbach | SC Freiburg | 0-6 | 3 - 6 - 5 |