Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 10/30/21 7:00 AM | 10/30/21 7:00 AM | FC Elche | Real Madrid | 1-2 | 2 - 5 points |
| 10/30/21 9:15 AM | 10/30/21 9:15 AM | FC Sevilla | CA Osasuna | 2-0 | 2 - 5 points |
| 10/30/21 11:30 AM | 10/30/21 11:30 AM | FC Valencia | FC Villarreal | 2-0 | 2 - 5 points |
| 10/30/21 2:00 PM | 10/30/21 2:00 PM | FC Barcelona | Deportivo Alaves | 1-1 | 2 - 5 points |
| 10/31/21 8:00 AM | 10/31/21 8:00 AM | FC Cadiz | RCD Mallorca | 1-1 | 2 - 5 points |
| 10/31/21 10:15 AM | 10/31/21 10:15 AM | Atletico Madrid | Real Betis Sevilla | 3-0 | 2 - 5 points |
| 10/31/21 12:30 PM | 10/31/21 12:30 PM | FC Getafe | Espanyol Barcelona | 2-1 | 2 - 5 points |
| 10/31/21 3:00 PM | 10/31/21 3:00 PM | Real Sociedad | Athletic Bilbao | 1-1 | 2 - 5 points |
| 11/1/21 12:30 PM | 11/1/21 12:30 PM | Rayo Vallecano | Celta Vigo | 0-0 | 2 - 5 points |
| 11/1/21 3:00 PM | 11/1/21 3:00 PM | UD Levante | FC Granada | 0-3 | 2 - 5 points |