Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 12/10/21 2:00 PM | 12/10/21 2:00 PM | RCD Mallorca | Celta Vigo | 0-0 | 2 - 5 points |
| 12/11/21 7:00 AM | 12/11/21 7:00 AM | Espanyol Barcelona | UD Levante | 4-3 | 2 - 5 points |
| 12/11/21 9:15 AM | 12/11/21 9:15 AM | Deportivo Alaves | FC Getafe | 1-1 | 2 - 5 points |
| 12/11/21 11:30 AM | 12/11/21 11:30 AM | FC Valencia | FC Elche | 2-1 | 2 - 5 points |
| 12/11/21 2:00 PM | 12/11/21 2:00 PM | Athletic Bilbao | FC Sevilla | 0-1 | 2 - 5 points |
| 12/12/21 7:00 AM | 12/12/21 7:00 AM | FC Villarreal | Rayo Vallecano | 2-0 | 2 - 5 points |
| 12/12/21 9:15 AM | 12/12/21 9:15 AM | CA Osasuna | FC Barcelona | 2-2 | 2 - 5 points |
| 12/12/21 11:30 AM | 12/12/21 11:30 AM | Real Betis Sevilla | Real Sociedad | 4-0 | 2 - 5 points |
| 12/12/21 2:00 PM | 12/12/21 2:00 PM | Real Madrid | Atletico Madrid | 2-0 | 2 - 5 points |
| 12/13/21 2:00 PM | 12/13/21 2:00 PM | FC Cadiz | FC Granada | 1-1 | 2 - 5 points |