Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 12/22/21 2:30 PM | 12/22/21 2:30 PM | Athletic Bilbao | Real Madrid | 1-2 | 2 - 5 points |
| 1/16/22 7:00 AM | 1/16/22 7:00 AM | FC Elche | FC Villarreal | 1-0 | 2 - 5 points |
| 1/18/22 1:00 PM | 1/18/22 1:00 PM | Real Betis Sevilla | Deportivo Alaves | 4-0 | 2 - 5 points |
| 1/18/22 2:30 PM | 1/18/22 2:30 PM | FC Cadiz | Espanyol Barcelona | 2-2 | 2 - 5 points |
| 1/19/22 12:00 PM | 1/19/22 12:00 PM | Celta Vigo | CA Osasuna | 2-0 | 2 - 5 points |
| 1/19/22 2:30 PM | 1/19/22 2:30 PM | FC Valencia | FC Sevilla | 1-1 | 2 - 5 points |
| 1/20/22 12:00 PM | 1/20/22 12:00 PM | FC Getafe | FC Granada | 4-2 | 2 - 5 points |
| 2/16/22 12:00 PM | 2/16/22 12:00 PM | Atletico Madrid | UD Levante | 0-1 | 2 - 5 points |
| 3/2/22 2:00 PM | 3/2/22 2:00 PM | RCD Mallorca | Real Sociedad | 0-2 | 2 - 5 points |
| 4/24/22 2:00 PM | 4/24/22 2:00 PM | FC Barcelona | Rayo Vallecano | 0-1 | 2 - 5 points |