Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 1/21/22 2:00 PM | 1/21/22 2:00 PM | Espanyol Barcelona | Real Betis Sevilla | 1-4 | 2 - 5 points |
| 1/22/22 7:00 AM | 1/22/22 7:00 AM | UD Levante | FC Cadiz | 0-2 | 2 - 5 points |
| 1/22/22 9:15 AM | 1/22/22 9:15 AM | FC Villarreal | RCD Mallorca | 3-0 | 2 - 5 points |
| 1/22/22 11:30 AM | 1/22/22 11:30 AM | FC Sevilla | Celta Vigo | 2-2 | 2 - 5 points |
| 1/22/22 2:00 PM | 1/22/22 2:00 PM | Atletico Madrid | FC Valencia | 3-2 | 2 - 5 points |
| 1/23/22 7:00 AM | 1/23/22 7:00 AM | FC Granada | CA Osasuna | 0-2 | 2 - 5 points |
| 1/23/22 9:15 AM | 1/23/22 9:15 AM | Real Madrid | FC Elche | 2-2 | 2 - 5 points |
| 1/23/22 11:30 AM | 1/23/22 11:30 AM | Rayo Vallecano | Athletic Bilbao | 0-1 | 2 - 5 points |
| 1/23/22 11:30 AM | 1/23/22 11:30 AM | Real Sociedad | FC Getafe | 0-0 | 2 - 5 points |
| 1/23/22 2:00 PM | 1/23/22 2:00 PM | Deportivo Alaves | FC Barcelona | 0-1 | 2 - 5 points |