Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 2/18/22 2:00 PM | 2/18/22 2:00 PM | FC Elche | Rayo Vallecano | 2-1 | 2 - 5 points |
| 2/19/22 7:00 AM | 2/19/22 7:00 AM | FC Granada | FC Villarreal | 1-4 | 2 - 5 points |
| 2/19/22 9:15 AM | 2/19/22 9:15 AM | CA Osasuna | Atletico Madrid | 0-3 | 2 - 5 points |
| 2/19/22 11:30 AM | 2/19/22 11:30 AM | FC Cadiz | FC Getafe | 1-1 | 2 - 5 points |
| 2/19/22 2:00 PM | 2/19/22 2:00 PM | Real Madrid | Deportivo Alaves | 3-0 | 2 - 5 points |
| 2/20/22 7:00 AM | 2/20/22 7:00 AM | Espanyol Barcelona | FC Sevilla | 1-1 | 2 - 5 points |
| 2/20/22 9:15 AM | 2/20/22 9:15 AM | FC Valencia | FC Barcelona | 1-4 | 2 - 5 points |
| 2/20/22 11:30 AM | 2/20/22 11:30 AM | Real Betis Sevilla | RCD Mallorca | 2-1 | 2 - 5 points |
| 2/20/22 2:00 PM | 2/20/22 2:00 PM | Athletic Bilbao | Real Sociedad | 4-0 | 2 - 5 points |
| 2/21/22 2:00 PM | 2/21/22 2:00 PM | Celta Vigo | UD Levante | 1-1 | 2 - 5 points |