Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 4/8/22 2:00 PM | 4/8/22 2:00 PM | FC Sevilla | FC Granada | 4-2 | 2 - 5 points |
| 4/9/22 7:00 AM | 4/9/22 7:00 AM | FC Cadiz | Real Betis Sevilla | 1-2 | 2 - 5 points |
| 4/9/22 9:15 AM | 4/9/22 9:15 AM | RCD Mallorca | Atletico Madrid | 1-0 | 2 - 5 points |
| 4/9/22 11:30 AM | 4/9/22 11:30 AM | FC Villarreal | Athletic Bilbao | 1-1 | 2 - 5 points |
| 4/9/22 2:00 PM | 4/9/22 2:00 PM | Real Madrid | FC Getafe | 2-0 | 2 - 5 points |
| 4/10/22 7:00 AM | 4/10/22 7:00 AM | CA Osasuna | Deportivo Alaves | 1-0 | 2 - 5 points |
| 4/10/22 9:15 AM | 4/10/22 9:15 AM | Espanyol Barcelona | Celta Vigo | 1-0 | 2 - 5 points |
| 4/10/22 11:30 AM | 4/10/22 11:30 AM | FC Elche | Real Sociedad | 1-2 | 2 - 5 points |
| 4/10/22 2:00 PM | 4/10/22 2:00 PM | UD Levante | FC Barcelona | 2-3 | 2 - 5 points |
| 4/11/22 2:00 PM | 4/11/22 2:00 PM | Rayo Vallecano | FC Valencia | 1-1 | 2 - 5 points |