Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 4/19/22 12:00 PM | 4/19/22 12:00 PM | RCD Mallorca | Deportivo Alaves | 2-1 | 2 - 5 points |
| 4/19/22 2:00 PM | 4/19/22 2:00 PM | Real Betis Sevilla | FC Elche | 0-1 | 2 - 5 points |
| 4/19/22 2:30 PM | 4/19/22 2:30 PM | FC Villarreal | FC Valencia | 2-0 | 2 - 5 points |
| 4/20/22 12:00 PM | 4/20/22 12:00 PM | Atletico Madrid | FC Granada | 0-0 | 2 - 5 points |
| 4/20/22 1:00 PM | 4/20/22 1:00 PM | Celta Vigo | FC Getafe | 0-2 | 2 - 5 points |
| 4/20/22 2:30 PM | 4/20/22 2:30 PM | CA Osasuna | Real Madrid | 1-3 | 2 - 5 points |
| 4/21/22 12:00 PM | 4/21/22 12:00 PM | Espanyol Barcelona | Rayo Vallecano | 0-1 | 2 - 5 points |
| 4/21/22 12:00 PM | 4/21/22 12:00 PM | UD Levante | FC Sevilla | 2-3 | 2 - 5 points |
| 4/21/22 1:00 PM | 4/21/22 1:00 PM | FC Cadiz | Athletic Bilbao | 2-3 | 2 - 5 points |
| 4/21/22 2:30 PM | 4/21/22 2:30 PM | Real Sociedad | FC Barcelona | 0-1 | 2 - 5 points |