Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 9/11/21 11:30 AM | 9/11/21 11:30 AM | UD Levante | Rayo Vallecano | 1-1 | 2 - 5 points |
| 9/11/21 2:00 PM | 9/11/21 2:00 PM | Athletic Bilbao | RCD Mallorca | 2-0 | 2 - 5 points |
| 9/12/21 7:00 AM | 9/12/21 7:00 AM | Espanyol Barcelona | Atletico Madrid | 1-2 | 2 - 5 points |
| 9/12/21 9:15 AM | 9/12/21 9:15 AM | CA Osasuna | FC Valencia | 1-4 | 2 - 5 points |
| 9/12/21 11:30 AM | 9/12/21 11:30 AM | FC Cadiz | Real Sociedad | 0-2 | 2 - 5 points |
| 9/12/21 2:00 PM | 9/12/21 2:00 PM | Real Madrid | Celta Vigo | 5-2 | 2 - 5 points |
| 9/13/21 1:00 PM | 9/13/21 1:00 PM | FC Getafe | FC Elche | 0-1 | 2 - 5 points |
| 9/13/21 3:00 PM | 9/13/21 3:00 PM | FC Granada | Real Betis Sevilla | 1-2 | 2 - 5 points |
| 12/21/21 12:00 PM | 12/21/21 12:00 PM | FC Villarreal | Deportivo Alaves | 5-2 | 2 - 5 points |
| 12/21/21 2:30 PM | 12/21/21 2:30 PM | FC Sevilla | FC Barcelona | 1-1 | 2 - 5 points |