Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 10/1/21 2:00 PM | 10/1/21 2:00 PM | Athletic Bilbao | Deportivo Alaves | 1-0 | 2 - 5 points |
| 10/2/21 7:00 AM | 10/2/21 7:00 AM | CA Osasuna | Rayo Vallecano | 1-0 | 2 - 5 points |
| 10/2/21 9:15 AM | 10/2/21 9:15 AM | RCD Mallorca | UD Levante | 1-0 | 2 - 5 points |
| 10/2/21 11:30 AM | 10/2/21 11:30 AM | FC Cadiz | FC Valencia | 0-0 | 2 - 5 points |
| 10/2/21 2:00 PM | 10/2/21 2:00 PM | Atletico Madrid | FC Barcelona | 2-0 | 2 - 5 points |
| 10/3/21 7:00 AM | 10/3/21 7:00 AM | FC Elche | Celta Vigo | 1-0 | 2 - 5 points |
| 10/3/21 9:15 AM | 10/3/21 9:15 AM | Espanyol Barcelona | Real Madrid | 2-1 | 2 - 5 points |
| 10/3/21 11:30 AM | 10/3/21 11:30 AM | FC Getafe | Real Sociedad | 1-1 | 2 - 5 points |
| 10/3/21 11:30 AM | 10/3/21 11:30 AM | FC Villarreal | Real Betis Sevilla | 2-0 | 2 - 5 points |
| 10/3/21 2:00 PM | 10/3/21 2:00 PM | FC Granada | FC Sevilla | 1-0 | 2 - 5 points |