Schedule
| Competition | Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|---|
| DFB | 8/6/21 1:45 PM | 8/6/21 1:45 PM | Dynamo Dresden | SC Paderborn 07 | 2-1 | 2 - 5 points |
| DFB | 8/6/21 1:45 PM | 8/6/21 1:45 PM | TSV 1860 Munich | SV Darmstadt 98 | 6-5a.PSO | 2 - 5 points |
| DFB | 8/7/21 8:30 AM | 8/7/21 8:30 AM | 1. FC Lokomotive Leipzig | Bayer 04 Leverkusen | 0-3 | 2 - 5 points |
| DFB | 8/7/21 8:30 AM | 8/7/21 8:30 AM | SV Sandhausen | RB Leipzig | 0-4 | 2 - 5 points |
| DFB | 8/7/21 8:30 AM | 8/7/21 8:30 AM | SpVgg Bayreuth | Arminia Bielefeld | 3-6 | 2 - 5 points |
| DFB | 8/7/21 8:30 AM | 8/7/21 8:30 AM | BFC Dynamo | VfB Stuttgart | 0-6 | 2 - 5 points |
| DFB | 8/7/21 8:30 AM | 8/7/21 8:30 AM | Greifswalder FC | FC Augsburg | 2-4 | 2 - 5 points |
| DFB | 8/7/21 8:30 AM | 8/7/21 8:30 AM | Wuppertaler SV | VfL Bochum | 1-2a.e.t | 2 - 5 points |
| DFB | 8/7/21 8:30 AM | 8/7/21 8:30 AM | VfL Osnabrück | Werder Bremen | 2-0 | 2 - 5 points |
| DFB | 8/7/21 8:30 AM | 8/7/21 8:30 AM | Eintracht Norderstedt | Hannover 96 | 0-4 | 2 - 5 points |
| DFB | 8/7/21 8:30 AM | 8/7/21 8:30 AM | SC Weiche Flensburg 08 | Holstein Kiel | 2-4a.e.t | 2 - 5 points |
| DFB | 8/7/21 11:30 AM | 8/7/21 11:30 AM | SV Babelsberg 03 | SpVgg Greuther Fürth | 7-6a.PSO | 2 - 5 points |
| DFB | 8/7/21 11:30 AM | 8/7/21 11:30 AM | 1. FC Magdeburg | FC St. Pauli | 2-3 | 2 - 5 points |
| DFB | 8/7/21 11:30 AM | 8/7/21 11:30 AM | SSV Ulm 1846 | 1. FC Nürnberg | 0-1 | 2 - 5 points |
| DFB | 8/7/21 1:45 PM | 8/7/21 1:45 PM | SV Wehen Wiesbaden | Borussia Dortmund | 0-3 | 2 - 5 points |
| DFB | 8/8/21 8:30 AM | 8/8/21 8:30 AM | FC Rot-Weiß Koblenz | Jahn Regensburg | 0-3 | 2 - 5 points |
| DFB | 8/8/21 8:30 AM | 8/8/21 8:30 AM | Türkgücü München | 1. FC Union Berlin | 0-1 | 2 - 5 points |
| DFB | 8/8/21 8:30 AM | 8/8/21 8:30 AM | SV Elversberg | FSV Mainz 05 | 9-10a.PSO | 2 - 5 points |
| DFB | 8/8/21 8:30 AM | 8/8/21 8:30 AM | FC Carl Zeiss Jena | 1. FC Köln | 3-5a.PSO | 2 - 5 points |
| DFB | 8/8/21 8:30 AM | 8/8/21 8:30 AM | SV Meppen | Hertha BSC | 0-1 | 2 - 5 points |
| DFB | 8/8/21 8:30 AM | 8/8/21 8:30 AM | SV Waldhof Mannheim | Eintracht Frankfurt | 2-0 | 2 - 5 points |
| DFB | 8/8/21 8:30 AM | 8/8/21 8:30 AM | VfL Oldenburg | Fortuna Düsseldorf | 0-5 | 2 - 5 points |
| DFB | 8/8/21 8:30 AM | 8/8/21 8:30 AM | FC 08 Villingen | FC Schalke 04 | 1-4 | 2 - 5 points |
| DFB | 8/8/21 8:30 AM | 8/8/21 8:30 AM | Preußen Münster | VfL Wolfsburg | 2-0 | 2 - 5 points |
| DFB | 8/8/21 11:30 AM | 8/8/21 11:30 AM | Eintracht Braunschweig | Hamburger SV | 1-2 | 2 - 5 points |
| DFB | 8/8/21 11:30 AM | 8/8/21 11:30 AM | FC Würzburger Kickers | SC Freiburg | 0-1 | 2 - 5 points |
| DFB | 8/8/21 11:30 AM | 8/8/21 11:30 AM | FC Hansa Rostock | 1. FC Heidenheim 1846 | 3-2a.e.t | 2 - 5 points |
| DFB | 8/9/21 11:30 AM | 8/9/21 11:30 AM | FC Viktoria Köln | 1899 Hoffenheim | 2-3a.e.t | 2 - 5 points |
| DFB | 8/9/21 11:30 AM | 8/9/21 11:30 AM | Sportfreunde Lotte | Karlsruher SC | 1-4 | 2 - 5 points |
| DFB | 8/9/21 11:30 AM | 8/9/21 11:30 AM | FC Ingolstadt | Erzgebirge Aue | 2-1 | 2 - 5 points |
| DFB | 8/9/21 1:45 PM | 8/9/21 1:45 PM | 1. FC Kaiserslautern | Bor. Mönchengladbach | 0-1 | 2 - 5 points |
| DFB | 8/25/21 1:15 PM | 8/25/21 1:15 PM | Bremer SV | FC Bayern Munich | 0-12 | 2 - 5 points |