Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 11/26/21 7:30 PM | 11/26/21 7:30 PM | VfB Stuttgart | FSV Mainz 05 | 2-1 | 6 - 4 - 5 |
| 11/27/21 2:30 PM | 11/27/21 2:30 PM | 1. FC Köln | Bor. Mönchengladbach | 4-1 | 5 - 6 - 4 |
| 11/27/21 2:30 PM | 11/27/21 2:30 PM | Hertha BSC | FC Augsburg | 1-1 | 4 - 6 - 5 |
| 11/27/21 2:30 PM | 11/27/21 2:30 PM | VfL Wolfsburg | Borussia Dortmund | 1-3 | 6 - 6 - 4 |
| 11/27/21 2:30 PM | 11/27/21 2:30 PM | SpVgg Greuther Fürth | 1899 Hoffenheim | 3-6 | 9 - 7 - 3 |
| 11/27/21 2:30 PM | 11/27/21 2:30 PM | VfL Bochum | SC Freiburg | 2-1 | 6 - 5 - 4 |
| 11/27/21 5:30 PM | 11/27/21 5:30 PM | FC Bayern Munich | Arminia Bielefeld | 1-0 | 3 - 9 - 9 |
| 11/28/21 2:30 PM | 11/28/21 2:30 PM | Eintracht Frankfurt | 1. FC Union Berlin | 2-1 | 4 - 4 - 7 |
| 11/28/21 4:30 PM | 11/28/21 4:30 PM | RB Leipzig | Bayer 04 Leverkusen | 1-3 | 4 - 7 - 6 |