Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 8/27/21 6:30 PM | 8/27/21 6:30 PM | Borussia Dortmund | 1899 Hoffenheim | 3-2 | 3 - 9 - 9 |
| 8/28/21 1:30 PM | 8/28/21 1:30 PM | FC Augsburg | Bayer 04 Leverkusen | 1-4 | 9 - 9 - 3 |
| 8/28/21 1:30 PM | 8/28/21 1:30 PM | FSV Mainz 05 | SpVgg Greuther Fürth | 3-0 | 3 - 9 - 9 |
| 8/28/21 1:30 PM | 8/28/21 1:30 PM | VfB Stuttgart | SC Freiburg | 2-3 | 4 - 5 - 6 |
| 8/28/21 1:30 PM | 8/28/21 1:30 PM | 1. FC Köln | VfL Bochum | 2-1 | 3 - 5 - 9 |
| 8/28/21 1:30 PM | 8/28/21 1:30 PM | Arminia Bielefeld | Eintracht Frankfurt | 1-1 | 9 - 7 - 3 |
| 8/28/21 4:30 PM | 8/28/21 4:30 PM | FC Bayern Munich | Hertha BSC | 5-0 | 3 - 9 - 9 |
| 8/29/21 1:30 PM | 8/29/21 1:30 PM | 1. FC Union Berlin | Bor. Mönchengladbach | 2-1 | 5 - 5 - 4 |
| 8/29/21 3:30 PM | 8/29/21 3:30 PM | VfL Wolfsburg | RB Leipzig | 1-0 | 7 - 7 - 4 |