Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 4/16/22 1:30 PM | 4/16/22 1:30 PM | FC Augsburg | Hertha BSC | 0-1 | 3 - 7 - 9 |
| 4/16/22 1:30 PM | 4/16/22 1:30 PM | FSV Mainz 05 | VfB Stuttgart | 0-0 | 4 - 7 - 8 |
| 4/16/22 1:30 PM | 4/16/22 1:30 PM | SC Freiburg | VfL Bochum | 3-0 | 3 - 8 - 9 |
| 4/16/22 1:30 PM | 4/16/22 1:30 PM | Borussia Dortmund | VfL Wolfsburg | 6-1 | 3 - 7 - 9 |
| 4/16/22 4:30 PM | 4/16/22 4:30 PM | Bor. Mönchengladbach | 1. FC Köln | 1-3 | 5 - 4 - 5 |
| 4/17/22 1:30 PM | 4/17/22 1:30 PM | Arminia Bielefeld | FC Bayern Munich | 0-3 | 9 - 9 - 3 |
| 4/17/22 3:30 PM | 4/17/22 3:30 PM | 1899 Hoffenheim | SpVgg Greuther Fürth | 0-0 | 3 - 9 - 9 |
| 4/17/22 3:30 PM | 4/17/22 3:30 PM | 1. FC Union Berlin | Eintracht Frankfurt | 2-0 | 4 - 6 - 6 |
| 4/17/22 5:30 PM | 4/17/22 5:30 PM | Bayer 04 Leverkusen | RB Leipzig | 0-1 | 5 - 5 - 5 |