| Date | Home | Away | Result |
|---|---|---|---|
| 1/21/25 11:45 AM | AS Monaco | Aston Villa | 1-0 |
| 1/21/25 11:45 AM | Atalanta Bergamo | SK Sturm Graz | 5-0 |
| 1/21/25 2:00 PM | Liverpool FC | OSC Lille | 2-1 |
| 1/21/25 2:00 PM | Atletico Madrid | Bayer 04 Leverkusen | 2-1 |
| 1/21/25 2:00 PM | Club Brugge | Juventus Turin | 0-0 |
| 1/21/25 2:00 PM | Red Star Belgrad | PSV Eindhoven | 2-3 |
| 1/21/25 2:00 PM | SK Slovan Bratislava | VfB Stuttgart | 1-3 |
| 1/21/25 2:00 PM | FC Bologna | Borussia Dortmund | 2-1 |
| 1/21/25 2:00 PM | Benfica Lisbon | FC Barcelona | 4-5 |
| 1/22/25 11:45 AM | Schachtjor Donezk | Stade Brest 29 | --- |
| 1/22/25 11:45 AM | RB Leipzig | Sporting Lisbon | --- |
| 1/22/25 2:00 PM | Arsenal FC | Dinamo Zagreb | --- |
| 1/22/25 2:00 PM | AC Milan | FC Girona | --- |
| 1/22/25 2:00 PM | Real Madrid | FC Red Bull Salzburg | --- |
| 1/22/25 2:00 PM | Paris St. Germain | Manchester City | --- |
| 1/22/25 2:00 PM | Celtic Glasgow | Young Boys Bern | --- |
| 1/22/25 2:00 PM | Feyenoord Rotterdam | FC Bayern Munich | --- |
| 1/22/25 2:00 PM | Sparta Prag | Inter Milan | --- |