| Date | Home | Away | Result |
|---|---|---|---|
| 1/10/25 1:00 PM | Fortuna Sittard | Go Ahead Eagles Deventer | --- |
| 1/11/25 9:30 AM | Heracles Almelo | Sparta Rotterdam | --- |
| 1/11/25 11:45 AM | Ajax Amsterdam | RKC Waalwijk | --- |
| 1/11/25 1:00 PM | PEC Zwolle | NEC Nijmwegen | --- |
| 1/11/25 2:00 PM | PSV Eindhoven | AZ Alkmaar | --- |
| 1/12/25 5:15 AM | FC Twente Enschede | Willem II Tilburg | --- |
| 1/12/25 7:30 AM | FC Groningen | Almere City FC | --- |
| 1/12/25 7:30 AM | Feyenoord Rotterdam | FC Utrecht | --- |
| 1/12/25 9:45 AM | NAC Breda | SC Heerenveen | --- |