| Eastern Conference | P | Pts | GF | GA | GD | w | d | l | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | Atlanta United FC | 17 | 39 | 36 | 14 | 22 | 12 | 3 | 2 |
| 2. | New York City FC | 17 | 38 | 34 | 16 | 18 | 11 | 5 | 1 |
| 3. | Philadelphia Union | 16 | 33 | 34 | 17 | 17 | 10 | 3 | 3 |
| 4. | Chicago Fire | 17 | 31 | 37 | 18 | 19 | 8 | 7 | 2 |
| 5. | Toronto FC | 17 | 31 | 34 | 26 | 8 | 9 | 4 | 4 |
| 6. | New York Red Bulls | 17 | 30 | 29 | 18 | 11 | 9 | 3 | 5 |
| 7. | New England Revolution | 17 | 28 | 23 | 19 | 4 | 8 | 4 | 5 |
| 8. | D.C. United | 17 | 27 | 25 | 22 | 3 | 7 | 6 | 4 |
| 9. | CF Montreal | 17 | 27 | 23 | 22 | 1 | 8 | 3 | 6 |
| 10. | Columbus Crew | 17 | 23 | 21 | 22 | -1 | 6 | 5 | 6 |
| 11. | Orlando City | 17 | 21 | 26 | 29 | -3 | 6 | 3 | 8 |
| 12. | Cincinnati FC | 17 | 12 | 15 | 36 | -21 | 3 | 3 | 11 |
| Western Conference | P | Pts | GF | GA | GD | w | d | l | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | Los Angeles FC | 17 | 42 | 48 | 20 | 28 | 13 | 3 | 1 |
| 2. | Real Salt Lake | 17 | 37 | 31 | 15 | 16 | 12 | 1 | 4 |
| 3. | Seattle Sounders | 17 | 37 | 34 | 21 | 13 | 11 | 4 | 2 |
| 4. | FC Dallas | 17 | 36 | 38 | 16 | 22 | 10 | 6 | 1 |
| 5. | Minnesota United FC | 17 | 36 | 29 | 13 | 16 | 10 | 6 | 1 |
| 6. | Houston Dynamo | 17 | 34 | 31 | 19 | 12 | 10 | 4 | 3 |
| 7. | Los Angeles Galaxy | 17 | 34 | 36 | 25 | 11 | 11 | 1 | 5 |
| 8. | San Jose Earthquakes | 17 | 32 | 32 | 20 | 12 | 10 | 2 | 5 |
| 9. | Colorado Rapids | 17 | 29 | 36 | 29 | 7 | 9 | 2 | 6 |
| 10. | Portland Timbers | 17 | 28 | 29 | 20 | 9 | 8 | 4 | 5 |
| 11. | Sporting Kansas City | 17 | 25 | 30 | 30 | 0 | 7 | 4 | 6 |
| 12. | Vancouver Whitecaps | 17 | 20 | 16 | 23 | -7 | 5 | 5 | 7 |