| Eastern Conference | P | Pts | GF | GA | GD | w | d | l | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | Cincinnati FC | 17 | 41 | 33 | 13 | 20 | 13 | 2 | 2 |
| 2. | Columbus Crew | 17 | 40 | 41 | 14 | 27 | 12 | 4 | 1 |
| 3. | New England Revolution | 17 | 40 | 37 | 16 | 21 | 12 | 4 | 1 |
| 4. | Philadelphia Union | 17 | 36 | 33 | 13 | 20 | 10 | 6 | 1 |
| 5. | Atlanta United FC | 17 | 34 | 42 | 21 | 21 | 10 | 4 | 3 |
| 6. | CF Montreal | 17 | 33 | 26 | 12 | 14 | 10 | 3 | 4 |
| 7. | Orlando City | 17 | 32 | 31 | 19 | 12 | 9 | 5 | 3 |
| 8. | Nashville SC | 17 | 31 | 25 | 13 | 12 | 9 | 4 | 4 |
| 9. | New York City FC | 17 | 30 | 23 | 16 | 7 | 8 | 6 | 3 |
| 10. | New York Red Bulls | 17 | 26 | 21 | 17 | 4 | 7 | 5 | 5 |
| 11. | Charlotte FC | 17 | 26 | 24 | 21 | 3 | 6 | 8 | 3 |
| 12. | Chicago Fire | 17 | 25 | 26 | 22 | 4 | 6 | 7 | 4 |
| 13. | D.C. United | 17 | 24 | 31 | 23 | 8 | 6 | 6 | 5 |
| 14. | Inter Miami CF | 17 | 23 | 25 | 21 | 4 | 6 | 5 | 6 |
| 15. | Toronto FC | 17 | 18 | 19 | 22 | -3 | 4 | 6 | 7 |
| Western Conference | P | Pts | GF | GA | GD | w | d | l | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | Houston Dynamo | 17 | 37 | 36 | 11 | 25 | 11 | 4 | 2 |
| 2. | St. Louis City SC | 17 | 35 | 41 | 17 | 24 | 11 | 2 | 4 |
| 3. | Los Angeles FC | 17 | 33 | 36 | 17 | 19 | 10 | 3 | 4 |
| 4. | San Jose Earthquakes | 17 | 31 | 25 | 16 | 9 | 8 | 7 | 2 |
| 5. | Vancouver Whitecaps | 17 | 30 | 35 | 19 | 16 | 8 | 6 | 3 |
| 6. | Portland Timbers | 17 | 30 | 29 | 22 | 7 | 9 | 3 | 5 |
| 7. | Sporting Kansas City | 17 | 29 | 30 | 21 | 9 | 9 | 2 | 6 |
| 8. | FC Dallas | 17 | 28 | 23 | 16 | 7 | 7 | 7 | 3 |
| 9. | Seattle Sounders | 17 | 27 | 19 | 11 | 8 | 7 | 6 | 4 |
| 10. | Austin FC | 17 | 25 | 28 | 22 | 6 | 7 | 4 | 6 |
| 11. | Los Angeles Galaxy | 17 | 24 | 31 | 29 | 2 | 6 | 6 | 5 |
| 12. | Real Salt Lake | 17 | 22 | 25 | 27 | -2 | 6 | 4 | 7 |
| 13. | Minnesota United FC | 17 | 21 | 24 | 20 | 4 | 4 | 9 | 4 |
| 14. | Colorado Rapids | 17 | 17 | 13 | 16 | -3 | 3 | 8 | 6 |