| Date | Home | Away | Result |
|---|---|---|---|
| 1/4/25 3:30 PM | Baltimore Ravens | Cleveland Browns | 35-10 |
| 1/4/25 7:00 PM | Pittsburgh Steelers | Cincinnati Bengals | 17-19 |
| 1/5/25 12:00 PM | Tennessee Titans | Houston Texans | 14-23 |
| 1/5/25 12:00 PM | Tampa Bay Buccaneers | New Orleans Saints | 27-19 |
| 1/5/25 12:00 PM | Indianapolis Colts | Jacksonville Jaguars | 26-23OT |
| 1/5/25 12:00 PM | New England Patriots | Buffalo Bills | 23-16 |
| 1/5/25 12:00 PM | Atlanta Falcons | Carolina Panthers | 38-44OT |
| 1/5/25 12:00 PM | Philadelphia Eagles | New York Giants | 20-13 |
| 1/5/25 12:00 PM | Dallas Cowboys | Washington Commanders | 19-23 |
| 1/5/25 12:00 PM | Green Bay Packers | Chicago Bears | 22-24 |
| 1/5/25 3:25 PM | Arizona Cardinals | San Francisco 49ers | 47-24 |
| 1/5/25 3:25 PM | Denver Broncos | Kansas City Chiefs | 38-0 |
| 1/5/25 3:25 PM | New York Jets | Miami Dolphins | 32-20 |
| 1/5/25 3:25 PM | Las Vegas Raiders | Los Angeles Chargers | 20-34 |
| 1/5/25 3:25 PM | Los Angeles Rams | Seattle Seahawks | 25-30 |
| 1/5/25 7:20 PM | Detroit Lions | Minnesota Vikings | 31-9 |