| Date | Home | Away | Result |
|---|---|---|---|
| 10/23/24 9:30 AM | Sporting Braga | FK Bodö/Glimt | --- |
| 10/23/24 9:30 AM | Galatasaray Istanbul | IF Elfsborg Boras | --- |
| 10/24/24 11:45 AM | AS Roma | Dynamo Kiew | --- |
| 10/24/24 11:45 AM | Eintracht Frankfurt | Rigas Futbola Skola | --- |
| 10/24/24 11:45 AM | Maccabi Tel Aviv | Real Sociedad | --- |
| 10/24/24 11:45 AM | Ferencvaros Budapest | OGC Nice | --- |
| 10/24/24 11:45 AM | PAOK Saloniki | Viktoria Plzen | --- |
| 10/24/24 11:45 AM | FC Midtjylland | Royale Union Saint-Gilloise | --- |
| 10/24/24 11:45 AM | Qarabag | Ajax Amsterdam | --- |
| 10/24/24 2:00 PM | Fenerbahce Istanbul | Manchester United | --- |
| 10/24/24 2:00 PM | Glasgow Rangers | FCSB Bukarest | --- |
| 10/24/24 2:00 PM | FC Porto | 1899 Hoffenheim | --- |
| 10/24/24 2:00 PM | Tottenham Hotspur | AZ Alkmaar | --- |
| 10/24/24 2:00 PM | Olympique Lyon | Besiktas Istanbul | --- |
| 10/24/24 2:00 PM | Malmö FF | Olympiakos Piräus | --- |
| 10/24/24 2:00 PM | FC Twente Enschede | Lazio Rom | --- |
| 10/24/24 2:00 PM | RSC Anderlecht | PFC Ludogorets Razgrad | --- |
| 10/24/24 2:00 PM | Athletic Bilbao | Slavia Prag | --- |