| Date | Home | Away | Result |
|---|---|---|---|
| 1/30/25 2:00 PM | FCSB Bukarest | Manchester United | --- |
| 1/30/25 2:00 PM | RSC Anderlecht | 1899 Hoffenheim | --- |
| 1/30/25 2:00 PM | Athletic Bilbao | Viktoria Plzen | --- |
| 1/30/25 2:00 PM | OGC Nice | FK Bodö/Glimt | --- |
| 1/30/25 2:00 PM | Olympique Lyon | PFC Ludogorets Razgrad | --- |
| 1/30/25 2:00 PM | FC Midtjylland | Fenerbahce Istanbul | --- |
| 1/30/25 2:00 PM | Dynamo Kiew | Rigas Futbola Skola | --- |
| 1/30/25 2:00 PM | FC Twente Enschede | Besiktas Istanbul | --- |
| 1/30/25 2:00 PM | AS Roma | Eintracht Frankfurt | --- |
| 1/30/25 2:00 PM | Glasgow Rangers | Royale Union Saint-Gilloise | --- |
| 1/30/25 2:00 PM | Slavia Prag | Malmö FF | --- |
| 1/30/25 2:00 PM | Tottenham Hotspur | IF Elfsborg Boras | --- |
| 1/30/25 2:00 PM | Maccabi Tel Aviv | FC Porto | --- |
| 1/30/25 2:00 PM | Ajax Amsterdam | Galatasaray Istanbul | --- |
| 1/30/25 2:00 PM | Ferencvaros Budapest | AZ Alkmaar | --- |
| 1/30/25 2:00 PM | Sporting Braga | Lazio Rom | --- |
| 1/30/25 2:00 PM | Olympiakos Piräus | Qarabag | --- |
| 1/30/25 2:00 PM | Real Sociedad | PAOK Saloniki | --- |