Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 3/9/22 11:45 AM | 3/9/22 11:45 AM | FC Porto | Olympique Lyon | 0-1 | 2 - 4 points |
| 3/9/22 11:45 AM | 3/9/22 11:45 AM | Real Betis Sevilla | Eintracht Frankfurt | 1-2 | 2 - 4 points |
| 3/10/22 11:45 AM | 3/10/22 11:45 AM | FC Sevilla | West Ham United | 1-0 | 2 - 4 points |
| 3/10/22 2:00 PM | 3/10/22 2:00 PM | FC Barcelona | Galatasaray Istanbul | 0-0 | 2 - 4 points |
| 3/10/22 2:00 PM | 3/10/22 2:00 PM | Sporting Braga | AS Monaco | 2-0 | 2 - 4 points |
| 3/10/22 2:00 PM | 3/10/22 2:00 PM | Glasgow Rangers | Red Star Belgrad | 3-0 | 2 - 4 points |
| 3/10/22 2:00 PM | 3/10/22 2:00 PM | Atalanta Bergamo | Bayer 04 Leverkusen | 3-2 | 2 - 4 points |