Schedule
| Competition | Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|---|
| NFL | 11/12/21 1:20 AM | 11/12/21 1:18 AM | Miami Dolphins | Baltimore Ravens | 22-10 | 5 - 25 points |
| NFL | 11/14/21 6:00 PM | 11/14/21 5:58 PM | New England Patriots | Cleveland Browns | 45-7 | 5 - 25 points |
| NFL | 11/14/21 6:00 PM | 11/14/21 5:58 PM | Pittsburgh Steelers | Detroit Lions | 16-16OT | 5 - 25 points |
| NFL | 11/14/21 6:00 PM | 11/14/21 5:58 PM | Indianapolis Colts | Jacksonville Jaguars | 23-17 | 5 - 25 points |
| NFL | 11/14/21 6:00 PM | 11/14/21 5:58 PM | Tennessee Titans | New Orleans Saints | 23-21 | 5 - 25 points |
| NFL | 11/14/21 6:00 PM | 11/14/21 5:58 PM | Dallas Cowboys | Atlanta Falcons | 43-3 | 5 - 25 points |
| NFL | 11/14/21 6:00 PM | 11/14/21 5:58 PM | Washington Football Team | Tampa Bay Buccaneers | 29-19 | 5 - 25 points |
| NFL | 11/14/21 6:00 PM | 11/14/21 5:58 PM | New York Jets | Buffalo Bills | 17-45 | 5 - 25 points |
| NFL | 11/14/21 9:05 PM | 11/14/21 9:03 PM | Arizona Cardinals | Carolina Panthers | 10-34 | 5 - 25 points |
| NFL | 11/14/21 9:05 PM | 11/14/21 9:03 PM | Los Angeles Chargers | Minnesota Vikings | 20-27 | 5 - 25 points |
| NFL | 11/14/21 9:25 PM | 11/14/21 9:23 PM | Green Bay Packers | Seattle Seahawks | 17-0 | 5 - 25 points |
| NFL | 11/14/21 9:25 PM | 11/14/21 9:23 PM | Denver Broncos | Philadelphia Eagles | 13-30 | 5 - 25 points |
| NFL | 11/15/21 1:20 AM | 11/15/21 1:18 AM | Las Vegas Raiders | Kansas City Chiefs | 14-41 | 5 - 25 points |
| NFL | 11/16/21 1:15 AM | 11/16/21 1:13 AM | San Francisco 49ers | Los Angeles Rams | 31-10 | 5 - 25 points |