Schedule
| Competition | Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|---|
| NFL | 10/29/21 12:20 AM | 10/29/21 12:18 AM | Arizona Cardinals | Green Bay Packers | 21-24 | 5 - 25 points |
| NFL | 10/31/21 5:00 PM | 10/31/21 4:58 PM | Buffalo Bills | Miami Dolphins | 26-11 | 5 - 25 points |
| NFL | 10/31/21 5:00 PM | 10/31/21 4:58 PM | Atlanta Falcons | Carolina Panthers | 13-19 | 5 - 25 points |
| NFL | 10/31/21 5:00 PM | 10/31/21 4:58 PM | Chicago Bears | San Francisco 49ers | 22-33 | 5 - 25 points |
| NFL | 10/31/21 5:00 PM | 10/31/21 4:58 PM | Detroit Lions | Philadelphia Eagles | 6-44 | 5 - 25 points |
| NFL | 10/31/21 5:00 PM | 10/31/21 4:58 PM | Cleveland Browns | Pittsburgh Steelers | 10-15 | 5 - 25 points |
| NFL | 10/31/21 5:00 PM | 10/31/21 4:58 PM | Houston Texans | Los Angeles Rams | 22-38 | 5 - 25 points |
| NFL | 10/31/21 5:00 PM | 10/31/21 4:58 PM | Indianapolis Colts | Tennessee Titans | 31-34OT | 5 - 25 points |
| NFL | 10/31/21 5:00 PM | 10/31/21 4:58 PM | New York Jets | Cincinnati Bengals | 34-31 | 5 - 25 points |
| NFL | 10/31/21 8:05 PM | 10/31/21 8:03 PM | Seattle Seahawks | Jacksonville Jaguars | 31-7 | 5 - 25 points |
| NFL | 10/31/21 8:05 PM | 10/31/21 8:03 PM | Los Angeles Chargers | New England Patriots | 24-27 | 5 - 25 points |
| NFL | 10/31/21 8:25 PM | 10/31/21 8:23 PM | New Orleans Saints | Tampa Bay Buccaneers | 36-27 | 5 - 25 points |
| NFL | 10/31/21 8:25 PM | 10/31/21 8:23 PM | Denver Broncos | Washington Football Team | 17-10 | 5 - 25 points |
| NFL | 11/1/21 12:20 AM | 11/1/21 12:18 AM | Minnesota Vikings | Dallas Cowboys | 16-20 | 5 - 25 points |
| NFL | 11/2/21 12:15 AM | 11/2/21 12:13 AM | Kansas City Chiefs | New York Giants | 20-17 | 5 - 25 points |