Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 10/6/22 7:15 PM | 10/6/22 7:15 PM | Denver Broncos | Indianapolis Colts | 9-12OT | 3 - 10 - 7 |
| 10/9/22 8:30 AM | 10/9/22 8:30 AM | Green Bay Packers | New York Giants | 22-27 | 3 - 10 - 10 |
| 10/9/22 12:00 PM | 10/9/22 12:00 PM | Buffalo Bills | Pittsburgh Steelers | 38-3 | 3 - 10 - 10 |
| 10/9/22 12:00 PM | 10/9/22 12:00 PM | Tampa Bay Buccaneers | Atlanta Falcons | 21-15 | 3 - 10 - 10 |
| 10/9/22 12:00 PM | 10/9/22 12:00 PM | Washington Commanders | Tennessee Titans | 17-21 | 6 - 10 - 3 |
| 10/9/22 12:00 PM | 10/9/22 12:00 PM | New Orleans Saints | Seattle Seahawks | 39-32 | 4 - 10 - 4 |
| 10/9/22 12:00 PM | 10/9/22 12:00 PM | New York Jets | Miami Dolphins | 40-17 | 6 - 10 - 3 |
| 10/9/22 12:00 PM | 10/9/22 12:00 PM | Cleveland Browns | Los Angeles Chargers | 28-30 | 6 - 10 - 3 |
| 10/9/22 12:00 PM | 10/9/22 12:00 PM | New England Patriots | Detroit Lions | 29-0 | 4 - 10 - 5 |
| 10/9/22 12:00 PM | 10/9/22 12:00 PM | Minnesota Vikings | Chicago Bears | 29-22 | 3 - 10 - 7 |
| 10/9/22 12:00 PM | 10/9/22 12:00 PM | Jacksonville Jaguars | Houston Texans | 6-13 | 3 - 10 - 10 |
| 10/9/22 3:05 PM | 10/9/22 3:05 PM | Carolina Panthers | San Francisco 49ers | 15-37 | 10 - 10 - 3 |
| 10/9/22 3:25 PM | 10/9/22 3:25 PM | Arizona Cardinals | Philadelphia Eagles | 17-20 | 5 - 10 - 3 |
| 10/9/22 3:25 PM | 10/9/22 3:25 PM | Los Angeles Rams | Dallas Cowboys | 10-22 | 3 - 10 - 7 |
| 10/9/22 7:20 PM | 10/9/22 7:20 PM | Baltimore Ravens | Cincinnati Bengals | 19-17 | 4 - 10 - 5 |
| 10/10/22 7:15 PM | 10/10/22 7:15 PM | Kansas City Chiefs | Las Vegas Raiders | 30-29 | 3 - 10 - 10 |