| Date | Home | Away | Result |
|---|---|---|---|
| 1/21/23 9:00 AM | SV Zulte-Waregem | KVC Westerlo | 1-1 |
| 1/21/23 11:15 AM | KV Oostende | KSV Cercle Brügge | 1-2 |
| 1/21/23 11:15 AM | KV Mechelen | KV Kortrijk | 3-2 |
| 1/21/23 1:45 PM | Royale Union Saint-Gilloise | OH Leuven | 1-0 |
| 1/22/23 6:30 AM | Royal Antwerp FC | Standard Liège | 4-1 |
| 1/22/23 9:00 AM | RFC Seraing | RSC Anderlecht | 0-1 |
| 1/22/23 11:30 AM | Club Brugge | Sporting Charleroi | 2-2 |
| 1/22/23 2:00 PM | Sint-Truidense VV | KAA Gent | 0-3 |
| 2/1/23 11:45 AM | KAS Eupen | KRC Genk | 1-1 |