Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 9/4/21 7:00 AM | 9/4/21 7:00 AM | Biarritz | Union Bordeaux Bègles | 27-15 | 10 - 10 - 3 |
| 9/4/21 9:05 AM | 9/4/21 9:05 AM | CA Brive | USA Perpignan | 36-15 | 3 - 10 - 10 |
| 9/4/21 9:05 AM | 9/4/21 9:05 AM | Castres Olympique | Section Paloise | 16-12 | 3 - 10 - 10 |
| 9/4/21 11:15 AM | 9/4/21 11:15 AM | Stade Français | Racing Métro 92 | 21-36 | 4 - 10 - 4 |
| 9/4/21 2:05 PM | 9/4/21 2:05 PM | RC Toulon | Montpellier Hérault RC | 24-24 | 3 - 10 - 7 |
| 9/5/21 10:45 AM | 9/5/21 10:45 AM | Lyon OU | ASM Clermont Auvergne | 28-19 | 3 - 10 - 6 |
| 9/5/21 2:05 PM | 9/5/21 2:05 PM | Atlantique Stade Rochelais | Stade Toulousain | 16-20 | 4 - 10 - 4 |