Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 11/27/21 8:00 AM | 11/27/21 8:00 AM | Biarritz | Stade Français | 17-14 | 3 - 10 - 6 |
| 11/27/21 8:00 AM | 11/27/21 8:00 AM | USA Perpignan | ASM Clermont Auvergne | 26-24 | 5 - 10 - 4 |
| 11/27/21 8:00 AM | 11/27/21 8:00 AM | Montpellier Hérault RC | Castres Olympique | 25-24 | 3 - 10 - 10 |
| 11/27/21 8:00 AM | 11/27/21 8:00 AM | Atlantique Stade Rochelais | Section Paloise | 36-8 | 3 - 10 - 10 |
| 11/27/21 10:00 AM | 11/27/21 10:00 AM | RC Toulon | Lyon OU | 19-13 | 4 - 10 - 5 |
| 11/27/21 2:05 PM | 11/27/21 2:05 PM | Stade Toulousain | CA Brive | 18-11 | 3 - 10 - 10 |
| 11/28/21 2:05 PM | 11/28/21 2:05 PM | Racing Métro 92 | Union Bordeaux Bègles | 14-37 | 3 - 10 - 7 |