Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 12/4/21 8:00 AM | 12/4/21 8:00 AM | ASM Clermont Auvergne | Biarritz | 39-11 | 3 - 10 - 10 |
| 12/4/21 8:00 AM | 12/4/21 8:00 AM | Montpellier Hérault RC | USA Perpignan | 30-6 | 3 - 10 - 10 |
| 12/4/21 8:00 AM | 12/4/21 8:00 AM | Lyon OU | CA Brive | 41-0 | 3 - 10 - 10 |
| 12/4/21 8:00 AM | 12/4/21 8:00 AM | Castres Olympique | Racing Métro 92 | 25-3 | 4 - 10 - 5 |
| 12/4/21 10:00 AM | 12/4/21 10:00 AM | Section Paloise | RC Toulon | 16-16 | 3 - 10 - 5 |
| 12/4/21 2:05 PM | 12/4/21 2:05 PM | Union Bordeaux Bègles | Stade Toulousain | 17-7 | 4 - 10 - 5 |
| 12/5/21 2:05 PM | 12/5/21 2:05 PM | Stade Français | Atlantique Stade Rochelais | 25-20 | 5 - 10 - 4 |