Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 2/5/22 8:00 AM | 2/5/22 8:00 AM | USA Perpignan | Stade Toulousain | 36-13 | 8 - 10 - 3 |
| 2/5/22 10:00 AM | 2/5/22 10:00 AM | Montpellier Hérault RC | Section Paloise | 29-12 | 3 - 10 - 10 |
| 2/5/22 10:00 AM | 2/5/22 10:00 AM | Racing Métro 92 | CA Brive | 57-19 | 3 - 10 - 10 |
| 2/5/22 10:00 AM | 2/5/22 10:00 AM | Lyon OU | Stade Français | 26-22 | 3 - 10 - 8 |
| 2/5/22 2:05 PM | 2/5/22 2:05 PM | RC Toulon | Castres Olympique | 10-22 | 3 - 10 - 8 |
| 2/6/22 2:05 PM | 2/6/22 2:05 PM | Biarritz | Atlantique Stade Rochelais | 27-24 | 10 - 10 - 3 |
| 3/13/22 3:05 PM | 3/13/22 3:05 PM | ASM Clermont Auvergne | Union Bordeaux Bègles | 29-26 | 3 - 10 - 6 |