Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 2/26/22 10:15 AM | 2/26/22 10:15 AM | Lyon OU | Biarritz | 34-15 | 3 - 10 - 10 |
| 2/26/22 10:15 AM | 2/26/22 10:15 AM | ASM Clermont Auvergne | USA Perpignan | 52-12 | 3 - 10 - 10 |
| 2/26/22 10:15 AM | 2/26/22 10:15 AM | Racing Métro 92 | Castres Olympique | 45-25 | 3 - 10 - 10 |
| 2/26/22 10:15 AM | 2/26/22 10:15 AM | Section Paloise | Atlantique Stade Rochelais | 16-22 | 4 - 10 - 5 |
| 2/26/22 2:05 PM | 2/26/22 2:05 PM | CA Brive | RC Toulon | 17-10 | 4 - 10 - 5 |
| 2/27/22 10:30 AM | 2/27/22 10:30 AM | Montpellier Hérault RC | Stade Français | 30-3 | 3 - 10 - 8 |
| 2/27/22 2:05 PM | 2/27/22 2:05 PM | Stade Toulousain | Union Bordeaux Bègles | 12-11 | 4 - 10 - 5 |