Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 10/2/21 8:00 AM | 10/2/21 8:00 AM | Lyon OU | Union Bordeaux Bègles | 15-20 | 3 - 10 - 10 |
| 10/2/21 8:00 AM | 10/2/21 8:00 AM | Montpellier Hérault RC | Atlantique Stade Rochelais | 21-11 | 4 - 10 - 4 |
| 10/2/21 8:00 AM | 10/2/21 8:00 AM | USA Perpignan | Section Paloise | 14-29 | 3 - 10 - 10 |
| 10/2/21 8:00 AM | 10/2/21 8:00 AM | CA Brive | Stade Français | 19-12 | 3 - 10 - 7 |
| 10/2/21 10:00 AM | 10/2/21 10:00 AM | Biarritz | Stade Toulousain | 11-17 | 7 - 10 - 3 |
| 10/2/21 2:05 PM | 10/2/21 2:05 PM | Castres Olympique | RC Toulon | 27-16 | 3 - 10 - 9 |
| 10/3/21 2:05 PM | 10/3/21 2:05 PM | ASM Clermont Auvergne | Racing Métro 92 | 26-17 | 3 - 10 - 6 |