Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 10/23/21 8:00 AM | 10/23/21 8:00 AM | Biarritz | CA Brive | 37-9 | 3 - 10 - 6 |
| 10/23/21 8:00 AM | 10/23/21 8:00 AM | ASM Clermont Auvergne | Section Paloise | 42-20 | 3 - 10 - 10 |
| 10/23/21 8:00 AM | 10/23/21 8:00 AM | Stade Français | Lyon OU | 23-18 | 4 - 10 - 4 |
| 10/23/21 8:00 AM | 10/23/21 8:00 AM | Union Bordeaux Bègles | USA Perpignan | 39-13 | 3 - 10 - 10 |
| 10/23/21 10:00 AM | 10/23/21 10:00 AM | Racing Métro 92 | Montpellier Hérault RC | 21-32 | 3 - 10 - 10 |
| 10/23/21 2:00 PM | 10/23/21 2:00 PM | Stade Toulousain | Castres Olympique | 41-0 | 3 - 10 - 10 |
| 10/24/21 2:05 PM | 10/24/21 2:05 PM | Atlantique Stade Rochelais | RC Toulon | 39-6 | 3 - 10 - 10 |