Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 10/30/21 8:00 AM | 10/30/21 8:00 AM | RC Toulon | Biarritz | 13-9 | 3 - 10 - 10 |
| 10/30/21 8:00 AM | 10/30/21 8:00 AM | USA Perpignan | Atlantique Stade Rochelais | 22-13 | 6 - 10 - 3 |
| 10/30/21 8:00 AM | 10/30/21 8:00 AM | Castres Olympique | CA Brive | 23-22 | 3 - 10 - 10 |
| 10/30/21 8:00 AM | 10/30/21 8:00 AM | Section Paloise | Stade Français | 18-9 | 3 - 10 - 5 |
| 10/30/21 10:00 AM | 10/30/21 10:00 AM | Montpellier Hérault RC | Lyon OU | 30-8 | 3 - 10 - 6 |
| 10/30/21 2:05 PM | 10/30/21 2:05 PM | Union Bordeaux Bègles | ASM Clermont Auvergne | 25-9 | 3 - 10 - 8 |
| 10/31/21 3:05 PM | 10/31/21 3:05 PM | Racing Métro 92 | Stade Toulousain | 27-18 | 4 - 10 - 5 |