Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 10/15/21 2:00 PM | 10/15/21 2:00 PM | SD Eibar | UD Almeria | 1-0 | 5 - 7 points |
| 10/16/21 9:00 AM | 10/16/21 9:00 AM | FC Girona | SD Huesca | 1-3 | 5 - 7 points |
| 10/16/21 9:00 AM | 10/16/21 9:00 AM | SD Amorebieta | FC Cartagena | 2-3 | 5 - 7 points |
| 10/16/21 11:15 AM | 10/16/21 11:15 AM | UD Las Palmas | CD Teneriffa | 2-1 | 5 - 7 points |
| 10/16/21 1:30 PM | 10/16/21 1:30 PM | FC Malaga | Real Saragossa | 1-1 | 5 - 7 points |
| 10/16/21 2:00 PM | 10/16/21 2:00 PM | Sporting Gijon | AD Alcorcon | 1-0 | 5 - 7 points |
| 10/17/21 7:00 AM | 10/17/21 7:00 AM | UD Ibiza Eivissa | CD Mirandes | 0-2 | 5 - 7 points |
| 10/17/21 9:00 AM | 10/17/21 9:00 AM | CD Leganes | Real Valladolid | 0-2 | 5 - 7 points |
| 10/17/21 11:15 AM | 10/17/21 11:15 AM | Burgos CF | CD Lugo | 1-1 | 5 - 7 points |
| 10/17/21 11:15 AM | 10/17/21 11:15 AM | Real Sociedad B | Real Oviedo | 1-1 | 5 - 7 points |
| 10/17/21 2:00 PM | 10/17/21 2:00 PM | SD Ponferradina | CF Fuenlabrada | 0-0 | 5 - 7 points |