Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 10/22/21 2:00 PM | 10/22/21 2:00 PM | SD Eibar | FC Cartagena | 2-1 | 5 - 7 points |
| 10/23/21 9:00 AM | 10/23/21 9:00 AM | UD Ibiza Eivissa | CF Fuenlabrada | 3-1 | 5 - 7 points |
| 10/23/21 11:15 AM | 10/23/21 11:15 AM | Sporting Gijon | Real Valladolid | 1-2 | 5 - 7 points |
| 10/23/21 1:30 PM | 10/23/21 1:30 PM | FC Malaga | CD Lugo | 1-0 | 5 - 7 points |
| 10/23/21 2:00 PM | 10/23/21 2:00 PM | CD Leganes | CD Teneriffa | 1-2 | 5 - 7 points |
| 10/24/21 7:00 AM | 10/24/21 7:00 AM | SD Amorebieta | Real Sociedad B | 1-2 | 5 - 7 points |
| 10/24/21 7:00 AM | 10/24/21 7:00 AM | CD Mirandes | UD Almeria | 1-4 | 5 - 7 points |
| 10/24/21 11:15 AM | 10/24/21 11:15 AM | SD Ponferradina | Real Oviedo | 1-2 | 5 - 7 points |
| 10/24/21 11:15 AM | 10/24/21 11:15 AM | Burgos CF | SD Huesca | 3-1 | 5 - 7 points |
| 10/24/21 2:00 PM | 10/24/21 2:00 PM | UD Las Palmas | AD Alcorcon | 3-0 | 5 - 7 points |
| 10/25/21 2:00 PM | 10/25/21 2:00 PM | FC Girona | Real Saragossa | 1-1 | 5 - 7 points |