Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 12/10/21 2:00 PM | 12/10/21 2:00 PM | Sporting Gijon | SD Huesca | 1-1 | 5 - 7 points |
| 12/11/21 9:00 AM | 12/11/21 9:00 AM | UD Ibiza Eivissa | FC Girona | 1-1 | 5 - 7 points |
| 12/11/21 9:00 AM | 12/11/21 9:00 AM | Burgos CF | CF Fuenlabrada | 2-0 | 5 - 7 points |
| 12/11/21 11:15 AM | 12/11/21 11:15 AM | UD Almeria | Real Saragossa | 3-0 | 5 - 7 points |
| 12/11/21 1:30 PM | 12/11/21 1:30 PM | SD Eibar | FC Malaga | 2-2 | 5 - 7 points |
| 12/11/21 2:00 PM | 12/11/21 2:00 PM | CD Teneriffa | CD Lugo | 1-1 | 5 - 7 points |
| 12/12/21 7:00 AM | 12/12/21 7:00 AM | CD Leganes | SD Ponferradina | 1-1 | 5 - 7 points |
| 12/12/21 9:00 AM | 12/12/21 9:00 AM | Real Valladolid | Real Oviedo | 2-1 | 5 - 7 points |
| 12/12/21 11:15 AM | 12/12/21 11:15 AM | AD Alcorcon | FC Cartagena | 1-1 | 5 - 7 points |
| 12/12/21 11:15 AM | 12/12/21 11:15 AM | SD Amorebieta | UD Las Palmas | 1-1 | 5 - 7 points |
| 12/13/21 2:00 PM | 12/13/21 2:00 PM | CD Mirandes | Real Sociedad B | 2-0 | 5 - 7 points |