Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 2/18/22 2:00 PM | 2/18/22 2:00 PM | FC Cartagena | Real Valladolid | 2-3 | 5 - 7 points |
| 2/19/22 9:00 AM | 2/19/22 9:00 AM | Real Saragossa | UD Las Palmas | 2-1 | 5 - 7 points |
| 2/19/22 11:15 AM | 2/19/22 11:15 AM | FC Girona | SD Eibar | 0-1 | 5 - 7 points |
| 2/19/22 11:15 AM | 2/19/22 11:15 AM | CD Teneriffa | UD Ibiza Eivissa | 2-0 | 5 - 7 points |
| 2/19/22 2:00 PM | 2/19/22 2:00 PM | Real Sociedad B | FC Malaga | 2-0 | 5 - 7 points |
| 2/20/22 7:00 AM | 2/20/22 7:00 AM | CF Fuenlabrada | AD Alcorcon | 2-2 | 5 - 7 points |
| 2/20/22 9:00 AM | 2/20/22 9:00 AM | Burgos CF | Real Oviedo | 0-1 | 5 - 7 points |
| 2/20/22 11:15 AM | 2/20/22 11:15 AM | SD Huesca | CD Lugo | 1-0 | 5 - 7 points |
| 2/20/22 11:15 AM | 2/20/22 11:15 AM | Sporting Gijon | SD Ponferradina | 2-3 | 5 - 7 points |
| 2/20/22 2:00 PM | 2/20/22 2:00 PM | UD Almeria | CD Mirandes | 2-1 | 5 - 7 points |
| 2/21/22 2:00 PM | 2/21/22 2:00 PM | SD Amorebieta | CD Leganes | 1-3 | 5 - 7 points |