Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 2/25/22 2:00 PM | 2/25/22 2:00 PM | UD Almeria | CF Fuenlabrada | 3-1 | 5 - 7 points |
| 2/26/22 9:00 AM | 2/26/22 9:00 AM | UD Ibiza Eivissa | SD Huesca | 2-1 | 5 - 7 points |
| 2/26/22 9:00 AM | 2/26/22 9:00 AM | CD Mirandes | CD Teneriffa | 2-1 | 5 - 7 points |
| 2/26/22 11:15 AM | 2/26/22 11:15 AM | Real Oviedo | Real Sociedad B | 0-1 | 5 - 7 points |
| 2/26/22 2:00 PM | 2/26/22 2:00 PM | UD Las Palmas | CD Lugo | 2-2 | 5 - 7 points |
| 2/27/22 7:00 AM | 2/27/22 7:00 AM | SD Eibar | Burgos CF | 2-0 | 5 - 7 points |
| 2/27/22 9:00 AM | 2/27/22 9:00 AM | Sporting Gijon | Real Saragossa | 1-2 | 5 - 7 points |
| 2/27/22 11:15 AM | 2/27/22 11:15 AM | Real Valladolid | SD Amorebieta | 5-1 | 5 - 7 points |
| 2/27/22 11:15 AM | 2/27/22 11:15 AM | CD Leganes | FC Girona | 1-1 | 5 - 7 points |
| 2/27/22 2:00 PM | 2/27/22 2:00 PM | AD Alcorcon | SD Ponferradina | 2-2 | 5 - 7 points |
| 2/28/22 2:00 PM | 2/28/22 2:00 PM | FC Malaga | FC Cartagena | 1-1 | 5 - 7 points |