Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 4/15/22 11:30 AM | 4/15/22 11:30 AM | SD Eibar | UD Las Palmas | 2-2 | 5 - 7 points |
| 4/15/22 2:00 PM | 4/15/22 2:00 PM | SD Amorebieta | CD Mirandes | 1-0 | 5 - 7 points |
| 4/16/22 9:00 AM | 4/16/22 9:00 AM | CD Leganes | FC Malaga | 0-3 | 5 - 7 points |
| 4/16/22 11:15 AM | 4/16/22 11:15 AM | Real Valladolid | UD Almeria | 2-2 | 5 - 7 points |
| 4/16/22 1:30 PM | 4/16/22 1:30 PM | Sporting Gijon | Real Oviedo | 0-1 | 5 - 7 points |
| 4/16/22 2:00 PM | 4/16/22 2:00 PM | FC Cartagena | AD Alcorcon | 3-1 | 5 - 7 points |
| 4/17/22 7:00 AM | 4/17/22 7:00 AM | SD Ponferradina | CD Lugo | 3-1 | 5 - 7 points |
| 4/17/22 9:00 AM | 4/17/22 9:00 AM | Burgos CF | UD Ibiza Eivissa | 2-1 | 5 - 7 points |
| 4/17/22 11:15 AM | 4/17/22 11:15 AM | SD Huesca | Real Saragossa | 1-1 | 5 - 7 points |
| 4/17/22 11:15 AM | 4/17/22 11:15 AM | CD Teneriffa | CF Fuenlabrada | 3-1 | 5 - 7 points |
| 4/18/22 12:00 PM | 4/18/22 12:00 PM | FC Girona | Real Sociedad B | 2-0 | 5 - 7 points |