Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 12/14/21 11:30 AM | 12/14/21 8:30 AM | VfB Stuttgart | FC Bayern Munich | 0-5 | 1 - 3 points |
| 12/14/21 1:30 PM | 12/14/21 8:30 AM | Arminia Bielefeld | VfL Bochum | 2-0 | 1 - 3 points |
| 12/14/21 1:30 PM | 12/14/21 8:30 AM | FSV Mainz 05 | Hertha BSC | 4-0 | 1 - 3 points |
| 12/14/21 1:30 PM | 12/14/21 8:30 AM | VfL Wolfsburg | 1. FC Köln | 2-3 | 1 - 3 points |
| 12/15/21 11:30 AM | 12/14/21 8:30 AM | Bor. Mönchengladbach | Eintracht Frankfurt | 2-3 | 1 - 3 points |
| 12/15/21 1:30 PM | 12/14/21 8:30 AM | FC Augsburg | RB Leipzig | 1-1 | 1 - 3 points |
| 12/15/21 1:30 PM | 12/14/21 8:30 AM | 1. FC Union Berlin | SC Freiburg | 0-0 | 1 - 3 points |
| 12/15/21 1:30 PM | 12/14/21 8:30 AM | Bayer 04 Leverkusen | 1899 Hoffenheim | 2-2 | 1 - 3 points |
| 12/15/21 1:30 PM | 12/14/21 8:30 AM | Borussia Dortmund | SpVgg Greuther Fürth | 3-0 | 1 - 3 points |