| Date | Home | Away | Result |
|---|---|---|---|
| 10/15/22 6:30 AM | Rotherham United | Huddersfield Town | 2-1 |
| 10/15/22 6:30 AM | Luton Town | Queens Park Rangers | 3-1 |
| 10/15/22 9:00 AM | Middlesbrough FC | Blackburn Rovers | 1-2 |
| 10/15/22 9:00 AM | Bristol City | Millwall FC | 1-2 |
| 10/15/22 9:00 AM | Cardiff City | Coventry City | 0-1 |
| 10/15/22 9:00 AM | AFC Sunderland | Wigan Athletic | 2-1 |
| 10/15/22 9:00 AM | Preston North End | Stoke City | 0-2 |
| 10/15/22 9:00 AM | Sheffield United | FC Blackpool | 3-3 |
| 10/15/22 9:00 AM | Reading FC | West Bromwich Albion | 0-2 |
| 10/15/22 9:00 AM | Burnley FC | Swansea City | 4-0 |
| 10/15/22 1:45 PM | Watford FC | Norwich City | 2-1 |
| 10/16/22 9:00 AM | Hull City A.F.C. | Birmingham City | 0-2 |