| Date | Home | Away | Result |
|---|---|---|---|
| 9/13/22 1:45 PM | Swansea City | Sheffield United | 0-1 |
| 9/13/22 1:45 PM | Middlesbrough FC | Cardiff City | 2-3 |
| 9/13/22 1:45 PM | Blackburn Rovers | Watford FC | 2-0 |
| 9/13/22 1:45 PM | Hull City A.F.C. | Stoke City | 0-3 |
| 9/13/22 1:45 PM | Huddersfield Town | Wigan Athletic | 1-2 |
| 9/13/22 2:00 PM | Preston North End | Burnley FC | 1-1 |
| 9/14/22 1:45 PM | Rotherham United | FC Blackpool | 3-0 |
| 9/14/22 1:45 PM | Millwall FC | Queens Park Rangers | 0-2 |
| 9/14/22 1:45 PM | Norwich City | Bristol City | 3-2 |
| 9/14/22 1:45 PM | Luton Town | Coventry City | 2-2 |
| 9/14/22 2:00 PM | Reading FC | AFC Sunderland | 0-3 |
| 9/14/22 2:00 PM | West Bromwich Albion | Birmingham City | 2-3 |