| Date | Home | Away | Result |
|---|---|---|---|
| 10/22/22 6:30 AM | FC Blackpool | Preston North End | 4-2 |
| 10/22/22 9:00 AM | Blackburn Rovers | Birmingham City | 2-1 |
| 10/22/22 9:00 AM | Rotherham United | Hull City A.F.C. | 2-4 |
| 10/22/22 9:00 AM | Sheffield United | Norwich City | 2-2 |
| 10/22/22 9:00 AM | AFC Sunderland | Burnley FC | 2-4 |
| 10/22/22 9:00 AM | Middlesbrough FC | Huddersfield Town | 0-0 |
| 10/22/22 9:00 AM | Stoke City | Coventry City | 0-2 |
| 10/22/22 9:00 AM | Millwall FC | West Bromwich Albion | 2-1 |
| 10/22/22 9:00 AM | Reading FC | Bristol City | 2-0 |
| 10/22/22 9:00 AM | Queens Park Rangers | Wigan Athletic | 2-1 |
| 10/23/22 6:00 AM | Watford FC | Luton Town | 4-0 |
| 10/23/22 6:00 AM | Swansea City | Cardiff City | 2-0 |