| Date | Home | Away | Result |
|---|---|---|---|
| 11/1/22 2:45 PM | Hull City A.F.C. | Middlesbrough FC | 1-3 |
| 11/1/22 2:45 PM | Luton Town | Reading FC | 0-0 |
| 11/1/22 2:45 PM | Coventry City | Blackburn Rovers | 1-0 |
| 11/1/22 2:45 PM | Preston North End | Swansea City | 1-0 |
| 11/1/22 3:00 PM | West Bromwich Albion | FC Blackpool | 1-0 |
| 11/1/22 3:00 PM | Bristol City | Sheffield United | 0-1 |
| 11/2/22 2:45 PM | Wigan Athletic | Stoke City | 0-1 |
| 11/2/22 2:45 PM | Cardiff City | Watford FC | 1-2 |
| 11/2/22 2:45 PM | Birmingham City | Millwall FC | 0-0 |
| 11/2/22 2:45 PM | Huddersfield Town | AFC Sunderland | 0-2 |
| 11/2/22 2:45 PM | Norwich City | Queens Park Rangers | 0-0 |
| 11/2/22 2:45 PM | Burnley FC | Rotherham United | 3-2 |