| Date | Home | Away | Result |
|---|---|---|---|
| 11/4/22 3:00 PM | Reading FC | Preston North End | 1-2 |
| 11/5/22 7:30 AM | Sheffield United | Burnley FC | 5-2 |
| 11/5/22 10:00 AM | Stoke City | Birmingham City | 1-2 |
| 11/5/22 10:00 AM | FC Blackpool | Luton Town | 0-1 |
| 11/5/22 10:00 AM | Blackburn Rovers | Huddersfield Town | 1-0 |
| 11/5/22 10:00 AM | AFC Sunderland | Cardiff City | 0-1 |
| 11/5/22 10:00 AM | Watford FC | Coventry City | 0-1 |
| 11/5/22 10:00 AM | Middlesbrough FC | Bristol City | 1-1 |
| 11/5/22 10:00 AM | Rotherham United | Norwich City | 1-2 |
| 11/5/22 10:00 AM | Swansea City | Wigan Athletic | 2-2 |
| 11/5/22 10:00 AM | Queens Park Rangers | West Bromwich Albion | 0-1 |
| 11/5/22 10:00 AM | Millwall FC | Hull City A.F.C. | 0-0 |