Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 5/6/22 1:00 PM | 5/6/22 1:00 PM | Cambuur-Leeuwarden | RKC Waalwijk | 1-1 | 2 - 4 points |
| 5/7/22 11:45 AM | 5/7/22 11:45 AM | FC Twente Enschede | Fortuna Sittard | 1-2 | 2 - 4 points |
| 5/7/22 1:00 PM | 5/7/22 1:00 PM | PEC Zwolle | FC Utrecht | 1-1 | 2 - 4 points |
| 5/7/22 1:00 PM | 5/7/22 1:00 PM | Willem II Tilburg | Heracles Almelo | 2-0 | 2 - 4 points |
| 5/7/22 2:00 PM | 5/7/22 2:00 PM | FC Groningen | Sparta Rotterdam | 1-2 | 2 - 4 points |
| 5/8/22 5:15 AM | 5/8/22 5:15 AM | NEC Nijmwegen | Go Ahead Eagles Deventer | 1-0 | 2 - 4 points |
| 5/8/22 7:30 AM | 5/8/22 7:30 AM | AZ Alkmaar | Ajax Amsterdam | 2-2 | 2 - 4 points |
| 5/8/22 7:30 AM | 5/8/22 7:30 AM | Vitesse Arnheim | SC Heerenveen | 1-2 | 2 - 4 points |
| 5/8/22 9:45 AM | 5/8/22 9:45 AM | Feyenoord Rotterdam | PSV Eindhoven | 2-2 | 2 - 4 points |