Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 11/20/21 6:30 AM | 11/20/21 6:30 AM | Leicester City | Chelsea FC | 0-3 | 1 - 4 points |
| 11/20/21 9:00 AM | 11/20/21 9:00 AM | Wolverhampton Wanderers | West Ham United | 1-0 | 1 - 4 points |
| 11/20/21 9:00 AM | 11/20/21 9:00 AM | Burnley FC | Crystal Palace | 3-3 | 1 - 4 points |
| 11/20/21 9:00 AM | 11/20/21 9:00 AM | Newcastle United | Brentford FC | 3-3 | 1 - 4 points |
| 11/20/21 9:00 AM | 11/20/21 9:00 AM | Norwich City | Southampton FC | 2-1 | 1 - 4 points |
| 11/20/21 9:00 AM | 11/20/21 9:00 AM | Watford FC | Manchester United | 4-1 | 1 - 4 points |
| 11/20/21 9:00 AM | 11/20/21 9:00 AM | Aston Villa | Brighton and Hove Albion | 2-0 | 1 - 4 points |
| 11/20/21 11:30 AM | 11/20/21 11:30 AM | Liverpool FC | Arsenal FC | 4-0 | 1 - 4 points |
| 11/21/21 8:00 AM | 11/21/21 8:00 AM | Manchester City | Everton FC | 3-0 | 1 - 4 points |
| 11/21/21 10:30 AM | 11/21/21 10:30 AM | Tottenham Hotspur | Leeds United | 2-1 | 1 - 4 points |