Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 8/28/21 6:30 AM | 8/28/21 6:30 AM | Manchester City | Arsenal FC | 5-0 | 1 - 4 points |
| 8/28/21 9:00 AM | 8/28/21 9:00 AM | Newcastle United | Southampton FC | 2-2 | 1 - 4 points |
| 8/28/21 9:00 AM | 8/28/21 9:00 AM | Norwich City | Leicester City | 1-2 | 1 - 4 points |
| 8/28/21 9:00 AM | 8/28/21 9:00 AM | West Ham United | Crystal Palace | 2-2 | 1 - 4 points |
| 8/28/21 9:00 AM | 8/28/21 9:00 AM | Aston Villa | Brentford FC | 1-1 | 1 - 4 points |
| 8/28/21 9:00 AM | 8/28/21 9:00 AM | Brighton and Hove Albion | Everton FC | 0-2 | 1 - 4 points |
| 8/28/21 11:30 AM | 8/28/21 11:30 AM | Liverpool FC | Chelsea FC | 1-1 | 1 - 4 points |
| 8/29/21 8:00 AM | 8/29/21 8:00 AM | Tottenham Hotspur | Watford FC | 1-0 | 1 - 4 points |
| 8/29/21 8:00 AM | 8/29/21 8:00 AM | Burnley FC | Leeds United | 1-1 | 1 - 4 points |
| 8/29/21 10:30 AM | 8/29/21 10:30 AM | Wolverhampton Wanderers | Manchester United | 0-1 | 1 - 4 points |