Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 4/16/22 6:30 AM | 4/16/22 6:30 AM | Tottenham Hotspur | Brighton and Hove Albion | 0-1 | 1 - 4 points |
| 4/16/22 9:00 AM | 4/16/22 9:00 AM | Southampton FC | Arsenal FC | 1-0 | 1 - 4 points |
| 4/16/22 9:00 AM | 4/16/22 9:00 AM | Manchester United | Norwich City | 3-2 | 1 - 4 points |
| 4/16/22 9:00 AM | 4/16/22 9:00 AM | Watford FC | Brentford FC | 1-2 | 1 - 4 points |
| 4/17/22 8:15 AM | 4/17/22 8:15 AM | West Ham United | Burnley FC | 1-1 | 1 - 4 points |
| 4/17/22 8:15 AM | 4/17/22 8:15 AM | Newcastle United | Leicester City | 2-1 | 1 - 4 points |
| 5/10/22 2:00 PM | 5/10/22 2:00 PM | Aston Villa | Liverpool FC | 1-2 | 1 - 4 points |
| 5/11/22 1:30 PM | 5/11/22 1:30 PM | Leeds United | Chelsea FC | 0-3 | 1 - 4 points |
| 5/11/22 2:15 PM | 5/11/22 2:15 PM | Wolverhampton Wanderers | Manchester City | 1-5 | 1 - 4 points |
| 5/19/22 1:45 PM | 5/19/22 1:45 PM | Everton FC | Crystal Palace | 3-2 | 1 - 4 points |